Many social harms can involve students; Meanwhile, teenagers are a vulnerable group who are going through the critical period of puberty; In order to try to identify factors that reduce the risks of social harm for this group, considering the Iranian-Islamic background of teenagers, the role of Islamic lifestyle can be examined; The purpose of this research is to investigate the relationship between Islamic lifestyle and social harm in female students of the first year of high school. The statistical population of this research is the 8th grade female students of public schools in District 4 of Tabriz in the academic year of 2019-1400, the number of people in the population is 1896. The number of people in the sample is 313 and calculated using Morgan's table; The random sampling method is multi-stage; 5 schools of District 4 were randomly selected from each school with 3 classes. The measurement tool was a questionnaire of social harms and Islamic lifestyle, the research design is descriptive-correlation and its purpose is practical. Pearson's correlation coefficient test and multiple regression were used to check the research hypothesis. The research results show that there is a negative correlation between Islamic lifestyle and social harms; That is, with the increase in the use of the Islamic lifestyle in various social dimensions, science, etc., the amount of social damage, including theft, suicide, etc., decreases.